Antibody & Protein Arrays
Antibody & Protein Arrays
More Data, Less Sample
Many biological processes such as apoptosis, inflammation, angiogenesis, immune response and migration often accompany changes of cytokine expression levels. Because of the extensive cross-talk between cytokines, a complete analysis of biological responses and functions must be obtained through multiplex assays.
Antibody arrays provide a much broader view of protein activity than can be obtained with single-target ELISAs and Western blots. Moreover, antibody array screening improves the chances for discovering key factors, disease mechanisms or biomarkers related to cytokine signaling. Antibody arrays are spotted with immobilized antibodies, and are used for protein expression profiling.
Antibody arrays allow researchers to conduct rapid, accurate expression profiling of hundreds of cytokines, chemokines, growth factors, proteases, soluble receptors and other proteins from any biological fluid. A wide range of different array types is available from BioCat, see below.
To find all antibody arrays matching your antigens of interest easily, you can use RayBiotech's Array Picker Tool.
A Glass Slide Incubation Chamber and Frame (2, 4 or 16 wells) is provided for use with RayBio Glass Slide Arrays.
Profile up to 4,000 proteins on a single array using high-density antibody arrays (L-Series) and direct biotin labeling of proteins.
Analyze up to 1,000 biomarkers in one experiment using multiplex sandwich ELISA-based methodology.
Simultaneously quantify up to 1,000 cytokines with similar sensitivity as ELISA.
The identical antibody pairs used for the RayBiotech C- and G-series Cytokine Antibody Arrays and for the Quantibody Cytokine Antibody Arrays are contained in the corresponding ELISA kits recommended for array data validation.
To find the ELISA kit of your interest, please use our ELISA search tool.
RayBio Glycobiology Arrays are a versatile and innovative series of products designed to detect glycosylation. They are available in three different formats (Glycan Arrays, Glycome Arrays, Lectin Arrays) for detection of glycans or glycan-protein interactions. All 3 formats feature glass slide supports with fluorescent detection.
The term "Protein Arrays" is sometimes used interchangeably with "antibody arrays;" however, they are not the same thing. Protein arrays, in contrast to antibody arrays, are spotted with immobilized proteins to profile serological (auto)antibodies as well as study protein interactions with other proteins, peptides, DNA, and drugs.
BioCat offers semi-quantitative Protein Arrays for the following research fields: Allergen, Cancer, Autoimmune Disease. There are also options for customized arrays tailor-made to your individual needs.
RayPlex Bead Arrays
RayPlex Bead Arrays enable high-throughput multiplex protein detection in a wide variety of sample types using flow cytometry. RayPlex utilizes the sandwich immunoassay principle, wherein a target protein is immobilized between a capture antibody on a microbead and a fluorescently-conjugated detection antibody. By using different combinations of microbead sizes and fluorophores, multiple target proteins are analyzed simultaneously. RayPlex is compatible with most standard flow cytometers that are equipped with blue and red lasers capable of detecting fluorescence in the phycoerythrin (PE) and allophycocyanin (APC) channels, respectively.
Peptide Mapping Arrays
Peptide Mapping Arrays allow the profiling of immune responses in blood sera linked with infection (e.g. SARS-CoV-2), immunization, autoimmune diseases or cancer. They are also suitable for antibody epitope mapping or for identifying key residues for protein binding. To generate a peptide mapping array, overlapping peptides representing a full-length protein are spotted on a standard glass slide.