RNA m⁶A Methylase and Demethylase Activity Assays

N6-methyladenosine (m⁶A) is the most common and abundant modification on RNA molecules present in eukaryotes

BioCat offers kits for measuring total m⁶A demethylase activity/inhibition using nuclear extracts or purified m6A demethylases like FTO and ALKBH5 from a broad range of species. 

Fig.1. Reversible m⁶A methylation in DNA/RNA