Exosome Lipidomics and Metabolomics Services

Take your biomarker studies to the next level

• Discover novel circulating biomarkers
• Learn more about exosome biology
• Send us your sample and receive data in 5–6 weeks

Better understand the importance of lipid-based biomarkers and the roles lipids play in vesicle biogenesis and function with SBI’s Exosome Lipidomics Service. Exosomes were recently shown to have the highest lipid-to-protein ratio of all classes of extracellular vesicles. Simply send us your sample or purified exosomes and we’ll send back a spreadsheet with putative identifications, mass/charge ratios, and differential analysis. 

In addition to lipids, exosomes carry a wide range of metabolites that can also be used for biomarker discovery. Like exosomal lipids, exosomal metabolites can also take an active role in the target cell, and have been shown to reprogram metabolic machinery upon uptake by cancer cells, fueling growth (6). A recent study found distinctly different populations of metabolites in PANC1 cells treated with TGF-b, a known driver of cancer progression, versus a control group, suggesting that metabolite profiling can be used for differentiating cellular states.