3-D Life RGD Peptide
3-D Life Adhesion peptides are highly purified peptides containing motifs that can be recognized by cellular surface receptors. The peptides contain thiol groups for attachment to a hydrogel matrix. Matrix-bound adhesion peptides may confer cellular adhesion to the hydrogel matrix, which is a prerequisite for cellular growth, differentiation and survival of many cell types.User Manual Data sheet
RGD sequences are motifs on extracellular matrix proteins promoting adhesion to cellular integrin receptors. The 3-D Life RGD Peptide contains a RGD motif and a thiol group on the N-terminus. The thiol group is used to immobilize the peptide on thiol-reactive polymers in 3-D Life Hydrogels. The immobilized peptide promotes adhesion of cells carrying the appropriate integrin receptor.
Modification of 3-D Life Hydrogels with cell-adhesive properties. 3-D cell culture of cells requiring a cell-adhesive matrix based on the RGD motif.
*: Doa:8-amino-3,6-dioxaoctanoic acid