FADD Antibody

Datasheet
Specifications
Clonality: Polyclonal
Host: Rabbit
Reactivity: Human, mouse, rat, monkey
Applications: Western blot, Immunoprecipitation
Additional Information
Synonyms: FAS-associated death domain protein, GIG3, mgC8528, MORT1
Gene Symbol: FADD
Organism: Homo sapiens
Gene ID: 8772
UniProt ID: Q13158

Immunogen

Synthetic peptide surrounding amino acid 128 of human FADD

Application

Western blot analysis (0.5-4 ug/ml)and can also be used in immunoprecipitation. However, the optimal conditions should be determined individually. The antibody detects an ~28 kDa band, corresponding to the expected molecular mass of FADD on immunoblots.

Background

Fas-associating death domain containing protein (FADD), also known as mediator of receptor induced toxicity (MORT1), is a 23 kDa cytosolic protein with an apparent molecular weight of 28 kDa on SDS-PAGE. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas to initiate the apoptotic signalling cascade. Overexpression of FADD induces apoptosis.

  • Catalog Number
    3039-30T-BV
  • Supplier
    BioVision
  • Size
  • Shipping
    Blue Ice
  • Price
  • 220,00 €
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