myTags 80K Labeled Probe Set, 700 pmol
myTags® labeled probes from our partner Daicel Arbor Biosciences are a simple solution for producing successful hybridization to targets in FISH applicationsApplication Note Application Note 2
- Custom designed probes, specific only to genomic regions of interest
- Up to tens of thousands of probes per library
- Use immediately for labeling assays
- Probes bind only to intended targets, reducing background noise
- Range of fluorophores available for various microscopy filters
Due to the short size of the probes and the consistent melting temperature range, these probes are able to efficiently cross cell barriers and bind to their intended target in fluorescent in situ hybridization (FISH) applications. myTags® improve experimental results by reducing non-specific hybridization and background signal which typically occur with traditional BAC catalogFISH probes.
myTags® Labeled probes are delivered ready-to-use at a minimum yield of 700 pmol. The probes can be single- or triple-labeled with a fluorophore of choice, and we can offer assistance in selecting compatible fluorophore combinations for multi-color FISH or other applications requiring multiple fluorophores. For a triple-labeling please order the Triple-label Upgrade in addition. If a desired labeling option is not listed in our standard offering, please contact us for availability.
We offer free assistance in designing probes or self-designed probes can be incorporated into the myTags® labeling system.
For those who want to be more flexible in the choice of fluorophores or haptens and generate high-quality labeled probes themselves Arbor Biosciences offers myTags® Immortal Libraries which are amplifiable for endless probe supply.
- Beck, S. et al. (2018) Implications of CpG islands on chromosomal architectures and modes of global gene regulation. Nucleic Acids Research
- Braz, G.T. et al. (2018) Comparative Oligo-FISH Mapping: An Efficient and Powerful Methodology To Reveal Karyotypic and Chromosomal Evolution. Genetics
- Hou, L. et al. (2018) Chromosome painting and its applications in cultivated and wild rice. BMC Plant Biology
- Walczak, M. et al. (2018) ATG8 Is Essential Specifically for an Autophagy-Independent Function in Apicoplast Biogenesis in Blood-Stage Malaria Parasites. mBio
- Beagrie et al. (2017) Complex multi-enhancer contacts captured by genome architecture mapping. Nature
- Nozawa et al. (2017) SAF-A Regulates Interphase Chromosome Structure through Oligomerization with Chromatin-Associated RNAs. Cell
- Giorgetti et al. (2016) Structural organization of the inactive X chromosome in the mouse. Nature