Phospho-Cdc25C (Ser216) AntibodyDatasheet
|Applications:||WB, ELISA, IHC|
|Synonyms:||M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C|
Synthesized peptide derived from human Cdc25C around the phosphorylation site of S216.
WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.