Anti-ST2 Detection Antibody

Datasheet
Specifications
Clonality: Monoclonal
Host: Mouse
Reactivity: Human
Applications: CLIA,Lateral Flow,ELISA

Immunogen

Recombinant ST2

Background

Suppressor of tumorigenicity (ST2) belongs to the interleukin 1 family of receptors. It exists in two isoforms: soluble form (sST2) found circulating in the plasma and transmembrane receptor form (ST2L). This protein is expressed by cardiomyocytes and vascular endothelial cells. Binding of ST2L to its ligand IL-33, prevents hypertrophy of the myocardium and fibrosis. However, sST2 competes with ST2L to bind to IL-33 and upon binding its ligand, neutralizes the cardioprotective effects of IL-33 and ST2L. Elevated levels of sST2 are associated with ventricular remodeling, fibrosis and chronic heart failure.

  • Catalog Number
    A2099-100-BV
  • Supplier
    BioVision
  • Size
  • Shipping
    Blue Ice
  • Price
  • 401,00 €
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