Cynomolgus ACE2 / ACEH Protein, His Tag

Datasheet
Specifications
Molecular Weight: 85.7 kDa
Tag: His Tag
Source: Cynomolgus ACE2, His Tag (AC2-C52H7) is expressed from human 293 cells (HEK293). It contains AA Gln 18 - Thr 741 (Accession # A0A2K5X283-1).
Purity: >95% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Liquid
Additional Information
Synonyms: ACE-2,ACEH,ACE2
Organism: Monkey
Acc.No.: XP_005593094.1

Sequence Information

Gln 18 - Thr 741

Background

Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.

  • Catalog Number
    AC2-C52H7-1mg-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    Dry Ice
  • Price
  • 3.273,00 €
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