SARS-CoV-2 (COVID-19) NSP7&NSP8 Protein, His Tag

Datasheet
Specifications
Molecular Weight: 32.1 kDa
Tag: His Tag
Source: SARS-CoV-2 NSP7&NSP8, His Tag (NS8-C5125) is expressed from E.coli cells. It contains AA Ser 1 - Gln 83 (NSP7) & Ala 1 - Gln 198 (NSP8) (Accession # YP_009725303.1 (NSP7) & YP_009725304.1 (NSP8)).
Purity: >95% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Liquid
Additional Information
Synonyms: NSP7 & NSP8,nsp7 & nsp8
Organism: Other
Acc.No.: YP_009725303.1 (NSP7) & YP_009725304.1 (

Sequence Information

Ser 1 - Gln 83 (NSP7) & Ala 1 - Gln 198 (NSP8)

Background

During the formation of the coronaviral replication/transcription complex, essential steps include processing of the conserved polyprotein nsp7-10 region by the main protease Mpro and subsequent complex formation of the released nsp's. Upon infecting host cells, coronaviruses assemble a multi-subunit RNA-synthesis complex of viral non-structural proteins (nsp) responsible for the replication and transcription of the viral genome. non-structural proteins 7 (NSP7) forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.

  • Catalog Number
    NS8-C5125-100ug-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    Dry Ice
  • Price
  • 715,00 €
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