SARS-CoV-2 Nucleocapsid protein (D3L, S235F), His Tag, Variant Lineage B.1.1.7

Datasheet
Specifications
Molecular Weight: 47.4 kDa
Tag: His Tag
Source: SARS-CoV-2 Nucleocapsid protein, His Tag (NUN-C52H8) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (Accession # QHO62115.1). D3L/ R203K/ G204R/ S235F were identified in the SARS-CoV-2 Alpha variant (Pango lineage: B.1.1.7; other names: 20I/501Y.V1 or VOC 202012/01) (data retrieved from https://pubmed.ncbi.nlm.nih.gov/33095454/).
Purity: >90% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Powder
Additional Information
Synonyms: Nucleocapsid protein,NP,Protein N
Organism: Other
Acc.No.: QHO62115.1

Sequence Information

Met 1 - Ala 419

Background

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

  • Catalog Number
    NUN-C52H8-100ug-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    RT
  • Price
  • 476,00 €
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