The OpenSPR 2-Channel Instrument

OpenSPR is the world’s only benchtop surface plasmon resonance (SPR) instrument. It provides high quality, label-free interaction analysis for a fraction of the cost of existing solutions. Its unique nano-structured sensor surface uses localized SPR (LSPR) to deliver repeatable, highly sensitive kinetic data.

Rev4 Edit 2018

Application Note Application Note 2 Brochure

Product Description

Meet OpenSPR, the easy benchtop surface plasmon resonance system. Avoid costly & inconvenient SPR core facilities with this affordable benchtop SPR instrument and get complete in-depth label-free binding kinetics & affinity data in your own lab, within 1 hour!

Localized surface plasmon resonance (LSPR)

LSPR is generated by gold or silver nanoparticles, as compared to a continuous film of gold used in traditional SPR. Due to this, LSPR measures small changes in the wavelength of the absorbance position, rather than the angle as in SPR. With a smaller sensing volume, LSPR is more sensitive to molecular binding and less sensitive to bulk effects. In addition, it reduces artifacts caused by external variables such as temperature drift or buffer refractive index changes.

Moreover, LSPR is much less complex since no prism is needed, leaving you with a smaller and more affordable SPR system.

LSPR advantages with OpenSPR system

  • Smaller and more affordable system
  • More robust against vibration and mechanical noise
  • More repeatable and replicable kinetic data
  • No strict temperature control required
  • User-friendly with low maintenance

Flexible system with high accuracy and quality kinetics

The OpenSPR can be used for a wide variety of applications, from yes/no binding assays to complete kinetic/affinity characterization and many more. Due to a wide range of affordable sensor chips, you can customize this benchtop SPR system to your needs. It is compatible with a wide range of sample types and you need only a sample volume of 5–100 μL to receive highly consistent and sensitive kinetic data. Accuracy and quality of results are fully comparable to standard high-end SPR systems.


  • Kinetics/Affinity
  • Characterization Kinetics/Affinity Screening
  • Competition Assays Yes/No Binding
  • Concentration Analysis 
  • Thermodynamics
  • Epitope Mapping/Binning 

Comaptible with:

  • Proteins, Antibodies
  • Lipids, Carbohydrates
  • Nucleic Acids
  • Small Molecules
  • Cells, Viruses, Nanoparticles 
  • Catalog Number
  • Supplier
  • Size
  • Shipping
  • Price
  • 35.884,00 €
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you need any help?

Please contact:

Dr. Sieke Schaepe

Tel. +49 (0) 6221 71415 16