SARS-CoV-2 (COVID-19) Papain-like Protease Protein, His Tag

Molecular Weight: 37.6 kDa
Tag: His Tag
Source: SARS-CoV-2 Papain-like Protease, His Tag (PAE-C5148) is expressed from E.coli cells. It contains AA Glu 746 - Lys 1060 (Accession # YP_009725299.1).
Purity: >95% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Liquid
Additional Information
Synonyms: Papain-like Protease,Replicase polyprotein 1a,ORF1a polyprotein,pp1a,1a,PL-PRO,Plpro
Organism: Other
Acc.No.: YP_009725299.1

Sequence Information

Glu 746 - Lys 1060


New coronavirus is a single-stranded RNA positive-strand envelope type B coronavirus. Similar to the other two coronaviruses that cause SARS (Severe Acute Respiratory Syndrome) and MERS (Middle East Respiratory Syndrome), its genome encodes non-structural, structural, and accessory proteins. Non-structural proteins include 3-chymotrypsin-like protease (3CLpro), papain-like protease, helicase, and RNA-dependent RNA polymerase (RNA -dependent RNA polymerase (RdRp). Structural proteins include spike glycoproteins. Papain in coronavirus is the same as 3CLpro. This enzyme operates on no less than 11 cleavage sites on the large polyprotein 1ab. Processing of polyproteins translated from viral RNA is essential. Therefore, press this The activity of this enzyme will prevent virus imitation.

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