Biotinylated SARS-CoV-2 (COVID-19) S1 protein NTD, His,Avitag™
Datasheet| Specifications | |
|---|---|
| Molecular Weight: | 38.0 kDa |
| Tag: | His Tag & Avi Tag |
| Source: | Biotinylated SARS-CoV-2 S1 protein NTD, His,Avitag (S1D-C52E2) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Phe 318 (Accession # QHD43416.1). |
| Purity: | >90% as determined by SDS-PAGE. |
| Endotoxin Level: | Less than 1.0 EU per μg by the LAL method. |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | S1 protein NTD,Spike protein S1 NTD,BetaCoV S1-NTD |
| Organism: | Other |
| Acc.No.: | QHD43416.1 |
Sequence Information
Val 16 - Phe 318
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.