SARS-CoV-2 S1 protein NTD (L18F, D80A, D215G, 242-244del, R246I), His Tag (MALS verified), Variant Lineage B.1.351

Datasheet
Specifications
Molecular Weight: 34.5 kDa
Tag: His Tag
Source: SARS-CoV-2 S1 protein NTD, His Tag (S1D-C52Hc) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1). The L18F/D80A/D215G/LAL242-244del/R246I mutations were identified on the spike protein N-terminal domain (NTD) in the SARS-CoV-2 Beta variant (Pango lineage: B.1.351; other names: 20H/501Y.V2).
Purity: >90% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Powder
Additional Information
Synonyms: S1 protein NTD,Spike protein S1 NTD,BetaCoV S1-NTD
Organism: Other
Acc.No.: QHD43416.1

Sequence Information

Ser 13 - Leu 303

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

  • Catalog Number
    S1D-C52Hc-100ug-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    RT
  • Price
  • 476,00 €
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