SARS-CoV-2 S1 protein NTD (HV69-70del, Y144del), His Tag (MALS verified), Variant Lineage B.1.1.7

Datasheet
Specifications
Molecular Weight: 34.5 kDa
Tag: His Tag
Source: SARS-CoV-2 S1 protein NTD (HV69-70del, Y144del), His Tag (S1D-C52Hd) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1 (HV69-70del, Y144del)). The HV69-70del/Y144del mutations were identified on the spike protein N-terminal domain (NTD) in the SARS-CoV-2 Alpha variant (Pango lineage: B.1.1.7; other names: 20I/501Y.V1 or VOC 202012/01).
Purity: >90% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Powder
Additional Information
Synonyms: S1 protein NTD,Spike protein S1 NTD,BetaCoV S1-NTD
Organism: Other
Acc.No.: QHD43416.1 (HV69-70del, Y144del)

Sequence Information

Ser 13 - Leu 303

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

  • Catalog Number
    S1D-C52Hd-100ug-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    RT
  • Price
  • 476,00 €
Add to Cart