SARS-CoV-2 S1 protein NTD (L18F, T20N, P26S, D138Y, R190S), His Tag (MALS verified), Variant Lineage P.1

Datasheet
Specifications
Molecular Weight: 34.9 kDa
Tag: His Tag
Source: SARS-CoV-2 S1 protein NTD, His Tag (S1D-C52He) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1). The L18F/ T20N/ P26S/ D138Y/ R190S mutations were identified on the spike protein N-terminal domain (NTD) in the SARS-CoV-2 Gamma variant (Pango lineage: P.1; other names: 20J/501Y.V3).
Purity: >90% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Powder
Additional Information
Synonyms: S1 protein NTD,Spike protein S1 NTD,BetaCoV S1-NTD
Organism: Other
Acc.No.: QHD43416.1

Sequence Information

Ser 13 - Leu 303

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

  • Catalog Number
    S1D-C52He-1mg-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    RT
  • Price
  • 2.871,00 €
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