SARS-CoV-2 S1 protein (W152C, L452R, D614G), His Tag, Variant Lineage B.1.429

Datasheet
Specifications
Molecular Weight: 76.8 kDa
Tag: His Tag
Source: SARS-CoV-2 S1 protein (W152C, L452R, D614G), His Tag (S1N-C52Hs) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1 (W152C, L452R, D614G)). The mutations (W152C, L452R, D614G) were identified in the SARS-CoV-2 Epsilon variant (Pango lineage: B.1.427/B.1.429; other names: 20C/S:452R, or CAL.20C).
Purity: >95% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Powder
Additional Information
Synonyms: Spike,S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1
Organism: Other
Acc.No.: QHD43416.1 (W152C, L452R, D614G)

Sequence Information

Val 16 - Arg 685

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

  • Catalog Number
    S1N-C52Hs-25ug-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    RT
  • Price
  • 422,00 €
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