Biotinylated SARS-CoV-2 (COVID-19) S2 protein, His,Avitag™
Datasheet| Specifications | |
|---|---|
| Molecular Weight: | 61.5 kDa |
| Tag: | His Tag & Avi Tag |
| Source: | Biotinylated SARS-CoV-2 S2 protein, His,Avitag™ (S2N-C52E8) is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). |
| Purity: | >95% as determined by SDS-PAGE. |
| Endotoxin Level: | Less than 1.0 EU per μg by the LAL method. |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | Spike,S2 protein,Spike glycoprotein Subunit2,S glycoprotein Subunit2,Spike protein S2 |
| Organism: | Other |
| Acc.No.: | QHD43416.1 |
Sequence Information
Ser 686 - Pro 1213
Background
It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.