SARS-CoV-2 (COVID-19) S2 protein, His Tag

Datasheet
Specifications
Molecular Weight: 60.0 kDa
Tag: His Tag
Source: SARS-CoV-2 S2 protein, His Tag (S2N-C52H5) is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to prevent the formation of aggregates in the course of protein production.
Purity: >90% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Powder
Additional Information
Synonyms: Spike,S2 protein,Spike glycoprotein Subunit2,S glycoprotein Subunit2,Spike protein S2
Organism: Other
Acc.No.: QHD43416.1

Sequence Information

Ser 686 - Pro 1213

Background

It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

  • Catalog Number
    S2N-C52H5-100ug-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    RT
  • Price
  • 476,00 €
Add to Cart