SARS-CoV-2 Spike NTD, His Tag (B.1.1.529/Omicron) (MALS verified)

Datasheet
Specifications
Molecular Weight: 34.6 kDa
Tag: His Tag
Source: SARS-CoV-2 Spike NTD, His Tag (B.1.1.529/Omicron) (SPD-C522d) is expressed from human 293 cells (HEK293). It contains AA Ser 13 - Leu 303 (Accession # QHD43416.1 (A67V, HV69-70del, T95I, G142D, VYY143-145del, N211del, L212I, ins214EPE)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: B.1.1.529; GISAID clade: GR/484A; Nextstrain clade: 21K).
Purity: >95% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Powder
Additional Information
Synonyms: S1 protein NTD,Spike protein S1 NTD,BetaCoV S1-NTD
Organism: Other
Acc.No.: QHD43416.1 (A67V, HV69-70del, T95I, G142

Sequence Information

Ser 13 - Leu 303

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

  • Catalog Number
    SPD-C522d-100ug-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    RT
  • Price
  • 476,00 €
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