SARS-CoV-2 (COVID-19) S protein RBD (L452R), His Tag, Variant Lineage P.1
Datasheet| Specifications | |
|---|---|
| Molecular Weight: | 26.6 kDa |
| Tag: | His Tag |
| Source: | SARS-CoV-2 S protein RBD (L452R), His Tag (SPD-C52He) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537(L452R) (Accession # QHD43416.1(L452R)). |
| Purity: | >90% as determined by SDS-PAGE. |
| Endotoxin Level: | Less than 1.0 EU per μg by the LAL method. |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD |
| Organism: | Other |
| Acc.No.: | QHD43416.1(L452R) |
Sequence Information
Arg 319 - Lys 537(L452R)
Background
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.