SARS-CoV-2 (COVID-19) S protein RBD (E484K), His Tag (MALS verified), Variant Lineage B.1.351

Datasheet
Specifications
Molecular Weight: 26.5 kDa
Tag: His Tag
Source: SARS-CoV-2 S protein RBD (E484K), His Tag (SRD-C52H3) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (E484K)). E484K mutaion was identified in the SARS-CoV-2 Beta variant (Pango lineage: B.1.351; other names: 20H/501Y.V2).
Purity: >95% as determined by SDS-PAGE.
Endotoxin Level: Less than 1.0 EU per μg by the LAL method.
Format: Powder
Additional Information
Synonyms: Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD
Organism: Other
Acc.No.: QHD43416.1 (E484K)

Sequence Information

Arg 319 - Lys 537

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

  • Catalog Number
    SRD-C52H3-1mg-AC
  • Supplier
    ACROBiosystems
  • Size
  • Shipping
    RT
  • Price
  • 2.871,00 €
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