GW274150

Datasheet
Specifications
CAS Number: 210354-22-6
Formula: C8H17N3O2S
Format: Powder
Molecular Weight: 219.3
Purity: 98.00%

Description

GW274150 shows less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 is a selective and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 uM; Kd=40 nM) and rat iNOS (ED50=1.15 uM). GW274150 plays a protective role in an acute model of lung injury inflammation.

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