Eltanexor

Datasheet
Specifications
CAS Number: 1642300-52-4
Formula: C17H10F6N6O
Format: Powder
Molecular Weight: 428.29
Purity: 98.00%

Description

Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leukemic cell lines. Eltanexor is a second-generation, highly specific, and orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity.

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