T2R4 Expressing HEK293T Cell Line
|Cell Category:||Drug Discovery Cell Lines|
|Tissue of Origin:||Kidney|
|Marker:||Hygromycin resistance, expression of FLAG sequence at N-terminus of bitter taste receptors|
T2R4 Expressing HEK293T Cell Line was generated through the cloning of TAS2R gene into pcDNA 3.1+ (Hygromycin) vector between KpnI and NotI restriction sites. T2R4 Expressing HEK293T Cell Line allows for the structural and functional analysis of T2R receptors. Possible applications of T2R4 Expressing HEK293T Cell Line would be the development of bitter compound blockers or antagonists for these receptors.
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Genetically modified organism (GVO), see General Terms