T2R49 Expressing HEK293T Cell Line

Cell Category: Drug Discovery Cell Lines
Organism: Human
Tissue of Origin: Kidney
Morphology: Epithelial
Culture Properties: Adherent
Marker: Hygromycin resistance, expression of FLAG sequence at N-terminus of bitter taste receptors

Additional Information

T2R49 Expressing HEK293T Cell Line was generated through the cloning of TAS2R gene into pcDNA 3.1+ (Hygromycin) vector between KpnI and NotI restriction sites. T2R49 Expressing HEK293T Cell Line allows for the structural and functional analysis of T2R receptors. Possible applications of T2R49 Expressing HEK293T Cell Line would be the development of bitter compound blockers or antagonists for these receptors.

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Genetically modified organism (GVO), see General Terms

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